Difference between revisions of "YJL047C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL047C YJL047C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003583 YJL047C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTT101 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTT101 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:352103..349575
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|nowrap| Chr X:352108..349580
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003583
 
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'''Description of {{PAGENAME}}:''' Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p<ref name='S000080900'>Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 {{SGDpaper|S000080900}} PMID 15718301</ref><ref name='S000075344'>Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 {{SGDpaper|S000075344}} PMID 14519104</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37
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'''Description of YJL047C:''' Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex with a role in anaphase progression; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p<ref name='S000080900'>Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 {{SGDpaper|S000080900}} PMID 15718301</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000075344'>Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 {{SGDpaper|S000075344}} PMID 14519104</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37
 
  {{SGDpaper|S000073416}} PMID 12676951</ref>
 
  {{SGDpaper|S000073416}} PMID 12676951</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YJL047C
Gene name RTT101
Aliases CUL8, CULC
Feature type ORF, Verified
Coordinates Chr X:352108..349580
Primary SGDID S000003583


Description of YJL047C: Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex with a role in anaphase progression; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p[1][2][3][4]




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References

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  1. Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 SGD PMID 15718301
  2. Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 SGD PMID 19390089
  3. Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 SGD PMID 14519104
  4. Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 SGD PMID 12676951

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