Difference between revisions of "YJL047C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YJL047C
Gene name RTT101
Aliases CUL8, CULC
Feature type ORF, Verified
Coordinates Chr X:352103..349575


Description of YJL047C: Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p[1][2][3]




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Community Commentary

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References

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  1. Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 SGD PMID 15718301
  2. Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 SGD PMID 14519104
  3. Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 SGD PMID 12676951

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