Difference between revisions of "YJL041W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL041W YJL041W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003577 YJL041W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr X:365779..368368
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|nowrap| Chr X:365784..368373
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003577
 
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'''Description of {{PAGENAME}}:''' Essential component of the nuclear pore complex, which mediates nuclear import and export<ref name='S000068986'>Bailer SM, et al. (2001) The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport. Mol Cell Biol 21(23):7944-55 {{SGDpaper|S000068986}} PMID 11689687</ref><ref name='S000052968'>Fahrenkrog B, et al. (1998) Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes. J Cell Biol 143(3):577-88 {{SGDpaper|S000052968}} PMID 9813081</ref><ref name='S000047640'>Hurt EC (1988) A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae. EMBO J 7(13):4323-34
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'''Description of YJL041W:''' FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p)<ref name='S000068986'>Bailer SM, et al. (2001) The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport. Mol Cell Biol 21(23):7944-55 {{SGDpaper|S000068986}} PMID 11689687</ref><ref name='S000052968'>Fahrenkrog B, et al. (1998) Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes. J Cell Biol 143(3):577-88 {{SGDpaper|S000052968}} PMID 9813081</ref><ref name='S000145464'>Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 {{SGDpaper|S000145464}} PMID 19680227</ref><ref name='S000075041'>Grosshans H, et al. (2001) Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. J Cell Biol 153(4):745-62 {{SGDpaper|S000075041}} PMID 11352936</ref><ref name='S000047640'>Hurt EC (1988) A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae. EMBO J 7(13):4323-34 {{SGDpaper|S000047640}} PMID 3072197</ref><ref name='S000145463'>Jovanovic-Talisman T, et al. (2009) Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457(7232):1023-7 {{SGDpaper|S000145463}} PMID 19098896</ref><ref name='S000086510'>Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 {{SGDpaper|S000086510}} PMID 15741174</ref><ref name='S000043959'>Nehrbass U, et al. (1990) NSP1: a yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain. Cell 61(6):979-89 {{SGDpaper|S000043959}} PMID 2112428</ref><ref name='S000122438'>Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 {{SGDpaper|S000122438}} PMID 17418788</ref><ref name='S000052060'>Sharma K, et al. (1996) Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol 16(1):294-301 {{SGDpaper|S000052060}} PMID 8524308</ref><ref name='S000075845'>Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206
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J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 14:05, 19 June 2012

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Systematic name YJL041W
Gene name NSP1
Aliases
Feature type ORF, Verified
Coordinates Chr X:365784..368373
Primary SGDID S000003577


Description of YJL041W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p)[1][2][3][4][5][6][7][8][9][10][11]




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References

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  1. ↑ Bailer SM, et al. (2001) The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport. Mol Cell Biol 21(23):7944-55 SGD PMID 11689687
  2. ↑ Fahrenkrog B, et al. (1998) Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes. J Cell Biol 143(3):577-88 SGD PMID 9813081
  3. ↑ Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 SGD PMID 19680227
  4. ↑ Grosshans H, et al. (2001) Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. J Cell Biol 153(4):745-62 SGD PMID 11352936
  5. ↑ Hurt EC (1988) A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae. EMBO J 7(13):4323-34 SGD PMID 3072197
  6. ↑ Jovanovic-Talisman T, et al. (2009) Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457(7232):1023-7 SGD PMID 19098896
  7. ↑ Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 SGD PMID 15741174
  8. ↑ Nehrbass U, et al. (1990) NSP1: a yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain. Cell 61(6):979-89 SGD PMID 2112428
  9. ↑ Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
  10. ↑ Sharma K, et al. (1996) Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol 16(1):294-301 SGD PMID 8524308
  11. ↑ Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206 SGD PMID 15039779

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