YIR021W

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Systematic name YIR021W
Gene name MRS1
Aliases PET157
Feature type ORF, Verified
Coordinates Chr IX:397294..398385
Primary SGDID S000001460


Description of YIR021W: Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA[1][2][3]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [4] [5]





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References

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  1. Bassi GS, et al. (2002) Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A 99(1):128-33 SGD PMID 11773622
  2. Bousquet I, et al. (1990) Two group I mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing. Curr Genet 18(2):117-24 SGD PMID 1699677
  3. Kreike J, et al. (1986) Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiae. Curr Genet 11(3):185-91 SGD PMID 2834089
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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