Difference between revisions of "YIR021W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIR021W YIR021W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001460 YIR021W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MRS1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MRS1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IX:397291..398382
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|nowrap| Chr IX:397294..398385
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001460
 
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'''Description of {{PAGENAME}}:''' Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA<ref name='S000068996'>Bassi GS, et al. (2002) Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A 99(1):128-33 {{SGDpaper|S000068996}} PMID 11773622</ref><ref name='S000056613'>Bousquet I, et al. (1990) Two group I mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing. Curr Genet 18(2):117-24 {{SGDpaper|S000056613}} PMID 1699677</ref><ref name='S000055527'>Kreike J, et al. (1986) Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiae. Curr Genet 11(3):185-91
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'''Description of YIR021W:''' Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA<ref name='S000068996'>Bassi GS, et al. (2002) Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A 99(1):128-33 {{SGDpaper|S000068996}} PMID 11773622</ref><ref name='S000056613'>Bousquet I, et al. (1990) Two group I mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing. Curr Genet 18(2):117-24 {{SGDpaper|S000056613}} PMID 1699677</ref><ref name='S000055527'>Kreike J, et al. (1986) Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiae. Curr Genet 11(3):185-91
 
  {{SGDpaper|S000055527}} PMID 2834089</ref>
 
  {{SGDpaper|S000055527}} PMID 2834089</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YIR021W
Gene name MRS1
Aliases PET157
Feature type ORF, Verified
Coordinates Chr IX:397294..398385
Primary SGDID S000001460


Description of YIR021W: Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA[1][2][3]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [4] [5]





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References

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  1. Bassi GS, et al. (2002) Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A 99(1):128-33 SGD PMID 11773622
  2. Bousquet I, et al. (1990) Two group I mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing. Curr Genet 18(2):117-24 SGD PMID 1699677
  3. Kreike J, et al. (1986) Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiae. Curr Genet 11(3):185-91 SGD PMID 2834089
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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