Difference between revisions of "YIL143C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001405 YIL143C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SSL2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SSL2 '' | ||
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|nowrap| Chr IX:83041..80510 | |nowrap| Chr IX:83041..80510 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001405 |
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| − | '''Description of | + | '''Description of YIL143C:''' Component of RNA polymerase transcription factor TFIIH holoenzyme; has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; interacts functionally with TFIIB and has roles in transcription start site selection and in gene looping to juxtapose initiation and termination regions; involved in DNA repair; homolog of human ERCC3<ref name='S000040983'>Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75(7):1379-87 {{SGDpaper|S000040983}} PMID 8269516</ref><ref name='S000147458'>Goel S, et al. (2011) The mechanism of start site selection by RNA polymerase II: interplay between TFIIB and the Ssl2/XPB helicase subunit of TFIIH. J Biol Chem () {{SGDpaper|S000147458}} PMID 22081613</ref><ref name='S000053653'>Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80(1):21-8 {{SGDpaper|S000053653}} PMID 7813015</ref><ref name='S000041958'>Sweder KS and Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269(3):1852-7 |
| − | + | {{SGDpaper|S000041958}} PMID 8294433</ref> | |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL143C |
| Gene name | SSL2 |
| Aliases | LOM3, RAD25 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:83041..80510 |
| Primary SGDID | S000001405 |
Description of YIL143C: Component of RNA polymerase transcription factor TFIIH holoenzyme; has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; interacts functionally with TFIIB and has roles in transcription start site selection and in gene looping to juxtapose initiation and termination regions; involved in DNA repair; homolog of human ERCC3[1][2][3][4]
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Contents
Community Commentary
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References
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- ↑ Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75(7):1379-87 SGD PMID 8269516
- ↑ Goel S, et al. (2011) The mechanism of start site selection by RNA polymerase II: interplay between TFIIB and the Ssl2/XPB helicase subunit of TFIIH. J Biol Chem () SGD PMID 22081613
- ↑ Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80(1):21-8 SGD PMID 7813015
- ↑ Sweder KS and Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269(3):1852-7 SGD PMID 8294433
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