Difference between revisions of "YIL143C"

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'''Description of YIL143C:''' Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3<ref name='S000040983'>Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75(7):1379-87 {{SGDpaper|S000040983}} PMID 8269516</ref><ref name='S000041958'>Sweder KS and Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269(3):1852-7 {{SGDpaper|S000041958}} PMID 8294433</ref><ref name='S000053653'>Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80(1):21-8
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'''Description of YIL143C:''' Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3<ref name='S000040983'>Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75(7):1379-87 {{SGDpaper|S000040983}} PMID 8269516</ref><ref name='S000053653'>Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80(1):21-8 {{SGDpaper|S000053653}} PMID 7813015</ref><ref name='S000041958'>Sweder KS and Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269(3):1852-7
{{SGDpaper|S000053653}} PMID 7813015</ref>
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{{SGDpaper|S000041958}} PMID 8294433</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YIL143C
Gene name SSL2
Aliases LOM3, RAD25
Feature type ORF, Verified
Coordinates Chr IX:83041..80510
Primary SGDID S000001405


Description of YIL143C: Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3[1][2][3]




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References

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  1. Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75(7):1379-87 SGD PMID 8269516
  2. Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80(1):21-8 SGD PMID 7813015
  3. Sweder KS and Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269(3):1852-7 SGD PMID 8294433

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