Difference between revisions of "YIL140W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIL140W YIL140W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001402 YIL140W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AXL2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AXL2 ''
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|nowrap| Chr IX:85366..87837
 
|nowrap| Chr IX:85366..87837
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001402
 
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'''Description of {{PAGENAME}}:''' Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000053730'>Sanders SL, et al. (1999) O-Glycosylation of Axl2/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cells. J Cell Biol 145(6):1177-88 {{SGDpaper|S000053730}} PMID 10366591</ref><ref name='S000047396'>Roemer T, et al. (1996) Selection of axial growth sites in yeast requires Axl2p, a novel plasma membrane glycoprotein. Genes Dev 10(7):777-93
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'''Description of YIL140W:''' Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate<ref name='S000047396'>Roemer T, et al. (1996) Selection of axial growth sites in yeast requires Axl2p, a novel plasma membrane glycoprotein. Genes Dev 10(7):777-93 {{SGDpaper|S000047396}} PMID 8846915</ref><ref name='S000053730'>Sanders SL, et al. (1999) O-Glycosylation of Axl2/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cells. J Cell Biol 145(6):1177-88 {{SGDpaper|S000053730}} PMID 10366591</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
  {{SGDpaper|S000047396}} PMID 8846915</ref>
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  {{SGDpaper|S000074306}} PMID 14574415</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Protein Modification ====
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[[Category:Topic:Protein Details:Protein Modification]]
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'''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]]
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Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-27</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YIL140W
Gene name AXL2
Aliases BUD10, SRO4
Feature type ORF, Verified
Coordinates Chr IX:85366..87837
Primary SGDID S000001402


Description of YIL140W: Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate[1][2][3]




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Community Commentary

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Roemer T, et al. (1996) Selection of axial growth sites in yeast requires Axl2p, a novel plasma membrane glycoprotein. Genes Dev 10(7):777-93 SGD PMID 8846915
  2. Sanders SL, et al. (1999) O-Glycosylation of Axl2/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cells. J Cell Biol 145(6):1177-88 SGD PMID 10366591
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  4. submitted by Jeff Ubersax on 2004-01-27

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