Difference between revisions of "YIL121W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001383 YIL121W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''QDR2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''QDR2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:132244..133872 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001383 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001383 | ||
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| − | '''Description of YIL121W:''' Multidrug transporter required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake | + | '''Description of YIL121W:''' Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake<ref name='S000080433'>Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 {{SGDpaper|S000080433}} PMID 15649438</ref><ref name='S000076810'>Vargas RC, et al. (2004) Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant. Antimicrob Agents Chemother 48(7):2531-7 {{SGDpaper|S000076810}} PMID 15215105</ref><ref name='S000120124'>Vargas RC, et al. (2007) Saccharomyces cerevisiae Multidrug Resistance Transporter Qdr2 Is Implicated in Potassium Uptake, Providing a Physiological Advantage to Quinidine-Stressed Cells. Eukaryot Cell 6(2):134-42 |
| − | {{SGDpaper| | + | {{SGDpaper|S000120124}} PMID 17189489</ref> |
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL121W |
| Gene name | QDR2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:132244..133872 |
| Primary SGDID | S000001383 |
Description of YIL121W: Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake[1][2][3]
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References
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- ↑ Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 SGD PMID 15649438
- ↑ Vargas RC, et al. (2004) Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant. Antimicrob Agents Chemother 48(7):2531-7 SGD PMID 15215105
- ↑ Vargas RC, et al. (2007) Saccharomyces cerevisiae Multidrug Resistance Transporter Qdr2 Is Implicated in Potassium Uptake, Providing a Physiological Advantage to Quinidine-Stressed Cells. Eukaryot Cell 6(2):134-42 SGD PMID 17189489
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