YIL094C

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Systematic name YIL094C
Gene name LYS12
Aliases LYS10, LYS11
Feature type ORF, Verified
Coordinates Chr IX:187629..186514


Description of YIL094C: Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate[1]




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References

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  1. Strassman M and Ceci LN (1965) Enzymatic formation of alpha-ketoadipic acid from homoisocitric acid. J Biol Chem 240(11):4357-61 SGD PMID 4284830

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