YIL071C

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Systematic name YIL071C
Gene name PCI8
Aliases CSN11, YIH1, YIL071W
Feature type ORF, Verified
Coordinates Chr IX:229991..228657
Primary SGDID S000001333


Description of YIL071C: Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain[1][2]




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References

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  1. Shalev A, et al. (2001) Saccharomyces cerevisiae protein Pci8p and human protein eIF3e/Int-6 interact with the eIF3 core complex by binding to cognate eIF3b subunits. J Biol Chem 276(37):34948-57 SGD PMID 11457827
  2. Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563

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