YIL061C

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Systematic name YIL061C
Gene name SNP1
Aliases
Feature type ORF, Verified
Coordinates Chr IX:245556..244654
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Description of YIL061C: Component of U1 snRNP required for mRNA splicing via spliceosome; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein[1][2][3][4][5]



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References

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  1. Gunderson SI, et al. (1998) U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1(2):255-64 SGD PMID 9659922
  2. Kao HY and Siliciano PG (1992) The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene. Nucleic Acids Res 20(15):4009-13 SGD PMID 1387202
  3. Smith V and Barrell BG (1991) Cloning of a yeast U1 snRNP 70K protein homologue: functional conservation of an RNA-binding domain between humans and yeast. EMBO J 10(9):2627-34 SGD PMID 1714384
  4. Neubauer G, et al. (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90 SGD PMID 9012791
  5. Hilleren PJ, et al. (1995) The amino-terminal domain of yeast U1-70K is necessary and sufficient for function. Mol Cell Biol 15(11):6341-50 SGD PMID 7565787

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