Difference between revisions of "YIL061C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001323 YIL061C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SNP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SNP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:245559..244657 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001323 |
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| − | '''Description of | + | '''Description of YIL061C:''' Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein<ref name='S000136265'>Chen YC, et al. (2010) Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors. Mol Cell Biol 30(21):5245-56 {{SGDpaper|S000136265}} PMID 20823272</ref><ref name='S000076887'>Gunderson SI, et al. (1998) U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1(2):255-64 {{SGDpaper|S000076887}} PMID 9659922</ref><ref name='S000043875'>Hilleren PJ, et al. (1995) The amino-terminal domain of yeast U1-70K is necessary and sufficient for function. Mol Cell Biol 15(11):6341-50 {{SGDpaper|S000043875}} PMID 7565787</ref><ref name='S000056496'>Kao HY and Siliciano PG (1992) The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene. Nucleic Acids Res 20(15):4009-13 {{SGDpaper|S000056496}} PMID 1387202</ref><ref name='S000045702'>Neubauer G, et al. (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90 {{SGDpaper|S000045702}} PMID 9012791</ref><ref name='S000054305'>Smith V and Barrell BG (1991) Cloning of a yeast U1 snRNP 70K protein homologue: functional conservation of an RNA-binding domain between humans and yeast. EMBO J 10(9):2627-34 |
| − | {{SGDpaper| | + | {{SGDpaper|S000054305}} PMID 1714384</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with NAM7 [[Category:Two Hybrid Interactions with NAM7]]<br> | ||
| + | Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins <ref name='S000042824'>He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 {{SGDpaper|S000042824}} PMID 7883168</ref> <ref name = 'CAset9314-2003-04-30'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9314 Jurgen Wittmann] on 2003-04-30</ref> | ||
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| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Prp8 [[Category:Two Hybrid Interactions with Prp8]]<br> | ||
| + | Prp8 interacts with the U1snRNP protein Snp1 <ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref> <ref name = 'CAset9267-2003-04-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9267 Richard Grainger] on 2003-04-11</ref> | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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| + | <protect> | ||
==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL061C |
| Gene name | SNP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:245559..244657 |
| Primary SGDID | S000001323 |
Description of YIL061C: Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein[1][2][3][4][5][6]
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Community Commentary
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Interactions
Two Hybrid
Two Hybrid interaction with NAM7
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [7] [8]
Two Hybrid interaction with Prp8
Prp8 interacts with the U1snRNP protein Snp1 [9] [10]
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References
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- ↑ Chen YC, et al. (2010) Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors. Mol Cell Biol 30(21):5245-56 SGD PMID 20823272
- ↑ Gunderson SI, et al. (1998) U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1(2):255-64 SGD PMID 9659922
- ↑ Hilleren PJ, et al. (1995) The amino-terminal domain of yeast U1-70K is necessary and sufficient for function. Mol Cell Biol 15(11):6341-50 SGD PMID 7565787
- ↑ Kao HY and Siliciano PG (1992) The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene. Nucleic Acids Res 20(15):4009-13 SGD PMID 1387202
- ↑ Neubauer G, et al. (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90 SGD PMID 9012791
- ↑ Smith V and Barrell BG (1991) Cloning of a yeast U1 snRNP 70K protein homologue: functional conservation of an RNA-binding domain between humans and yeast. EMBO J 10(9):2627-34 SGD PMID 1714384
- ↑ He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168
- ↑ submitted by Jurgen Wittmann on 2003-04-30
- ↑ Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 SGD PMID 11425851
- ↑ submitted by Richard Grainger on 2003-04-11
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
