Difference between revisions of "YIL046W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIL046W YIL046W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001308 YIL046W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MET30 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MET30 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IX:268650..270572
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|nowrap| Chr IX:268651..270573
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001308
 
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'''Description of {{PAGENAME}}:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name='S000059458'>Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 {{SGDpaper|S000059458}} PMID 11027256</ref><ref name='S000042750'>Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94
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'''Description of YIL046W:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name='S000042750'>Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 {{SGDpaper|S000042750}} PMID 10637232</ref><ref name='S000059458'>Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52
  {{SGDpaper|S000042750}} PMID 10637232</ref>
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  {{SGDpaper|S000059458}} PMID 11027256</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Other Interactions ====
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[[Category:Topic:Interactions:Other Interactions]]
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'''Other Topic''': NOT Regulatory [[Category:Topic:NOT Regulatory]]
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Other Interactions interaction with SWE1 [[Category:Other Interactions Interactions with SWE1]]<br>
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Despite previous reports to the contrary, Met30p is not required for Swe1p degradation <ref name='S000071520'>McMillan JN, et al. (2002) Determinants of Swe1p degradation in Saccharomyces cerevisiae. Mol Biol Cell 13(10):3560-75 {{SGDpaper|S000071520}} PMID 12388757</ref> <ref name = 'CAset7236-2003-03-03'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7236 Daniel Lew] on 2003-03-03</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YIL046W
Gene name MET30
Aliases ZRG11
Feature type ORF, Verified
Coordinates Chr IX:268651..270573
Primary SGDID S000001308


Description of YIL046W: F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus[1][2]




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Community Commentary

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Interactions

Other Interactions

Other Topic: NOT Regulatory Other Interactions interaction with SWE1
Despite previous reports to the contrary, Met30p is not required for Swe1p degradation [3] [4]





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References

See Help:References on how to add references

  1. Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 SGD PMID 10637232
  2. Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 SGD PMID 11027256
  3. McMillan JN, et al. (2002) Determinants of Swe1p degradation in Saccharomyces cerevisiae. Mol Biol Cell 13(10):3560-75 SGD PMID 12388757
  4. submitted by Daniel Lew on 2003-03-03

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