YHR205W
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| Systematic name | YHR205W |
| Gene name | SCH9 |
| Aliases | KOM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:509363..511837 |
| Primary SGDID | S000001248 |
Description of YHR205W: Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB[1][2][3][4][5][6]
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References
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- ↑ Crauwels M, et al. (1997) The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway. Microbiology 143 ( Pt 8):2627-37 SGD PMID 9274016
- ↑ di Blasi F, et al. (1993) The SCH9 protein kinase mRNA contains a long 5' leader with a small open reading frame. Yeast 9(1):21-32 SGD PMID 8442384
- ↑ Morano KA and Thiele DJ (1999) The Sch9 protein kinase regulates Hsp90 chaperone complex signal transduction activity in vivo. EMBO J 18(21):5953-62 SGD PMID 10545107
- ↑ Fabrizio P, et al. (2001) Regulation of longevity and stress resistance by Sch9 in yeast. Science 292(5515):288-90 SGD PMID 11292860
- ↑ Prusty R and Keil RL (2004) SCH9, a putative protein kinase from Saccharomyces cerevisiae, affects HOT1-stimulated recombination. Mol Genet Genomics 272(3):264-74 SGD PMID 15349770
- ↑ Pascual-Ahuir A and Proft M (2007) The Sch9 kinase is a chromatin-associated transcriptional activator of osmostress-responsive genes. EMBO J 26(13):3098-108 SGD PMID 17568771
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