YHR171W
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| Systematic name | YHR171W | |
| Gene name | ATG7 | |
| Aliases | APG7, CVT2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VIII:445713..447605 | |
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Description of YHR171W: Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation.[1][2][3][4]
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References
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- ↑ Ichimura Y, et al. (2004) In vivo and in vitro reconstitution of atg8 conjugation essential for autophagy. J Biol Chem 279(39):40584-92 SGD PMID 15277523
- ↑ Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 SGD PMID 11100732
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
- ↑ Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 SGD PMID 9759731
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