Difference between revisions of "YHR149C"

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'''Description of {{PAGENAME}}:''' Protein of unknown function; found in the bud tip and bud neck, potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p<ref name='S000080360'>Tomishige N, et al. (2005) SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Yeast 22(2):141-55 {{SGDpaper|S000080360}} PMID 15645486</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000061434'>Drees BL, et al. (2001) A protein interaction map for cell polarity development. J Cell Biol 154(3):549-71
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'''Description of {{PAGENAME}}:''' Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p<ref name='S000119445'>Tomishige N, et al. (2005) SKG6, a suppressor gene of synthetic lethality of kex2Delta gas1Delta mutations, encodes a novel membrane protein showing polarized intracellular localization. J Gen Appl Microbiol 51(5):323-6 {{SGDpaper|S000119445}} PMID 16314687</ref><ref name='S000080360'>Tomishige N, et al. (2005) SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Yeast 22(2):141-55 {{SGDpaper|S000080360}} PMID 15645486</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000061434'>Drees BL, et al. (2001) A protein interaction map for cell polarity development. J Cell Biol 154(3):549-71
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YHR149C
Gene name SKG6
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:396662..394458


Description of YHR149C: Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p[1][2][3][4]




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Community Commentary

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [5]




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References

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  1. Tomishige N, et al. (2005) SKG6, a suppressor gene of synthetic lethality of kex2Delta gas1Delta mutations, encodes a novel membrane protein showing polarized intracellular localization. J Gen Appl Microbiol 51(5):323-6 SGD PMID 16314687
  2. Tomishige N, et al. (2005) SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Yeast 22(2):141-55 SGD PMID 15645486
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. Drees BL, et al. (2001) A protein interaction map for cell polarity development. J Cell Biol 154(3):549-71 SGD PMID 11489916
  5. submitted by Jeff Ubersax on 2004-01-27

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