Difference between revisions of "YHR136C"

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'''Description of YHR136C:''' Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation; overproduction suppresses a plc1 null mutation; GFP-fusion protein localizes to the cytoplasm<ref name='S000040619'>Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 {{SGDpaper|S000040619}} PMID 9475719</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000124179'>Wykoff DD, et al. (2007) Positive feedback regulates switching of phosphate transporters in S. cerevisiae. Mol Cell 27(6):1005-13
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'''Description of YHR136C:''' Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation; overproduction suppresses a plc1 null mutation; GFP-fusion protein localizes to the cytoplasm<ref name='S000124179'>Wykoff DD, et al. (2007) Positive feedback regulates switching of phosphate transporters in S. cerevisiae. Mol Cell 27(6):1005-13 {{SGDpaper|S000124179}} PMID 17889672</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000040619'>Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47
  {{SGDpaper|S000124179}} PMID 17889672</ref>
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  {{SGDpaper|S000040619}} PMID 9475719</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YHR136C
Gene name SPL2
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:375103..374657
Primary SGDID S000001178


Description of YHR136C: Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation; overproduction suppresses a plc1 null mutation; GFP-fusion protein localizes to the cytoplasm[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [4] [5]





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References

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  1. Wykoff DD, et al. (2007) Positive feedback regulates switching of phosphate transporters in S. cerevisiae. Mol Cell 27(6):1005-13 SGD PMID 17889672
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 SGD PMID 9475719
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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