YHR134W

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Systematic name YHR134W
Gene name WSS1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:371752..372561
Primary SGDID S000001176


Description of YHR134W: Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks[1][2][3][4]




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References

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  1. Birrell GW, et al. (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13 SGD PMID 11606770
  2. O'Neill BM, et al. (2004) Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response. Nucleic Acids Res 32(22):6519-30 SGD PMID 15598824
  3. Hannich JT, et al. (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280(6):4102-10 SGD PMID 15590687
  4. Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 SGD PMID 11606525

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