Difference between revisions of "YHR134W"

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'''Description of YHR134W:''' Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks<ref name='S000066115'>Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 {{SGDpaper|S000066115}} PMID 11606525</ref><ref name='S000081216'>Birrell GW, et al. (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13 {{SGDpaper|S000081216}} PMID 11606770</ref><ref name='S000080114'>Hannich JT, et al. (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280(6):4102-10 {{SGDpaper|S000080114}} PMID 15590687</ref><ref name='S000080171'>O'Neill BM, et al. (2004) Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response. Nucleic Acids Res 32(22):6519-30
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'''Description of YHR134W:''' Sumoylated protein that localizes to a single spot on the nuclear periphery of mother cells but not daughters; interacts genetically with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response<ref name='S000066115'>Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 {{SGDpaper|S000066115}} PMID 11606525</ref><ref name='S000081216'>Birrell GW, et al. (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13 {{SGDpaper|S000081216}} PMID 11606770</ref><ref name='S000080114'>Hannich JT, et al. (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280(6):4102-10 {{SGDpaper|S000080114}} PMID 15590687</ref><ref name='S000080171'>O'Neill BM, et al. (2004) Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response. Nucleic Acids Res 32(22):6519-30 {{SGDpaper|S000080171}} PMID 15598824</ref><ref name='S000125822'>van Heusden GP and Steensma HY (2008) The Saccharomyces cerevisiae Wss1 protein is only present in mother cells. FEMS Microbiol Lett 282(1):100-4
  {{SGDpaper|S000080171}} PMID 15598824</ref>
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  {{SGDpaper|S000125822}} PMID 18336552</ref>
 
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Revision as of 14:05, 2 December 2010

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Systematic name YHR134W
Gene name WSS1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:371752..372561
Primary SGDID S000001176


Description of YHR134W: Sumoylated protein that localizes to a single spot on the nuclear periphery of mother cells but not daughters; interacts genetically with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response[1][2][3][4][5]




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References

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  1. Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 SGD PMID 11606525
  2. Birrell GW, et al. (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13 SGD PMID 11606770
  3. Hannich JT, et al. (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280(6):4102-10 SGD PMID 15590687
  4. O'Neill BM, et al. (2004) Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response. Nucleic Acids Res 32(22):6519-30 SGD PMID 15598824
  5. van Heusden GP and Steensma HY (2008) The Saccharomyces cerevisiae Wss1 protein is only present in mother cells. FEMS Microbiol Lett 282(1):100-4 SGD PMID 18336552

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