YHR115C
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| Systematic name | YHR115C |
| Gene name | DMA1 |
| Aliases | CHF1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:341362..340112 |
| Primary SGDID | S000001157 |
Description of YHR115C: Protein involved in ubiquitin ligation; plays a role in regulating spindle position and orientation; functionally redundant with Dma2p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr.[1][2][3]
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References
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- ↑ Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 SGD PMID 15146058
- ↑ Loring GL, et al. (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105 SGD PMID 18202552
- ↑ Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11 SGD PMID 18171988
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