Difference between revisions of "YHR115C"

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'''Description of YHR115C:''' Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; homolog of S. pombe Dma1 and H. sapiens Chfr<ref name='S000077036'>Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810
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'''Description of YHR115C:''' Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr.<ref name='S000125080'>Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11 {{SGDpaper|S000125080}} PMID 18171988</ref><ref name='S000077036'>Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810
 
  {{SGDpaper|S000077036}} PMID 15146058</ref>
 
  {{SGDpaper|S000077036}} PMID 15146058</ref>
 
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Revision as of 14:05, 4 March 2008

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Systematic name YHR115C
Gene name DMA1
Aliases CHF1
Feature type ORF, Verified
Coordinates Chr VIII:341362..340112
Primary SGDID S000001157


Description of YHR115C: Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr.[1][2]




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References

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  1. Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11 SGD PMID 18171988
  2. Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 SGD PMID 15146058

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