Difference between revisions of "YHR077C"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR077C YHR077C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001119 YHR077C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NMD2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NMD2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VIII:255758..252376
 
|nowrap| Chr VIII:255758..252376
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001119
 
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'''Description of {{PAGENAME}}:''' Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000057529'>Cui Y, et al. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev 9(4):423-36 {{SGDpaper|S000057529}} PMID 7883167</ref><ref name='S000049623'>He F, et al. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol 17(3):1580-94 {{SGDpaper|S000049623}} PMID 9032286</ref><ref name='S000042824'>He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54
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'''Description of YHR077C:''' Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000057529'>Cui Y, et al. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev 9(4):423-36 {{SGDpaper|S000057529}} PMID 7883167</ref><ref name='S000049623'>He F, et al. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol 17(3):1580-94 {{SGDpaper|S000049623}} PMID 9032286</ref><ref name='S000042824'>He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54
 
  {{SGDpaper|S000042824}} PMID 7883168</ref>
 
  {{SGDpaper|S000042824}} PMID 7883168</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YHR077C
Gene name NMD2
Aliases IFS1, SUA1, UPF2
Feature type ORF, Verified
Coordinates Chr VIII:255758..252376
Primary SGDID S000001119


Description of YHR077C: Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance[1][2][3][4]




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Interactions

Two Hybrid

Two Hybrid interaction with NAM7
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [4] [5]





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References

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  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Cui Y, et al. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev 9(4):423-36 SGD PMID 7883167
  3. He F, et al. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol 17(3):1580-94 SGD PMID 9032286
  4. 4.0 4.1 He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168 Cite error: Invalid <ref> tag; name "S000042824" defined multiple times with different content
  5. submitted by Jurgen Wittmann on 2003-04-30

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