Difference between revisions of "YHR071W"

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'''Description of YHR071W:''' Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity<ref name='S000070425'>Shemer R, et al. (2002) Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5. Mol Cell Biol 22(15):5395-404 {{SGDpaper|S000070425}} PMID 12101234</ref><ref name='S000049533'>Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23
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'''Description of YHR071W:''' Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity<ref name='S000127803'>Aviram S, et al. (2008) Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation. Mol Cell Biol  {{SGDpaper|S000127803}} PMID 18794371</ref><ref name='S000070425'>Shemer R, et al. (2002) Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5. Mol Cell Biol 22(15):5395-404 {{SGDpaper|S000070425}} PMID 12101234</ref><ref name='S000049533'>Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23
 
  {{SGDpaper|S000049533}} PMID 9032248</ref>
 
  {{SGDpaper|S000049533}} PMID 9032248</ref>
 
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Revision as of 14:05, 15 October 2008

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Systematic name YHR071W
Gene name PCL5
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:237006..237695
Primary SGDID S000001113


Description of YHR071W: Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [4] [5]





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References

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  1. Aviram S, et al. (2008) Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation. Mol Cell Biol SGD PMID 18794371
  2. Shemer R, et al. (2002) Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5. Mol Cell Biol 22(15):5395-404 SGD PMID 12101234
  3. Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 SGD PMID 9032248
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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