YHR069C

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Systematic name YHR069C
Gene name RRP4
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:234660..233581
Primary SGDID S000001111


Description of YHR069C: Exosome non-catalytic core component; involved in 3'-5' exoribonuclease processing of rRNA and mRNA[1][2][3][4][5]




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References

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  1. Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 SGD PMID 17173052
  2. Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 SGD PMID 17174896
  3. Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
  4. Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
  5. Mitchell P, et al. (1996) The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes Dev 10(4):502-13 SGD PMID 8600032

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