Difference between revisions of "YHR069C"

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'''Description of YHR069C:''' 3'-5' exoribonuclease involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p<ref name='S000049705'>Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'--&gt;5' exoribonucleases. Cell 91(4):457-66 {{SGDpaper|S000049705}} PMID 9390555</ref><ref name='S000042474'>Mitchell P, et al. (1996) The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes Dev 10(4):502-13
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'''Description of YHR069C:''' Exosome non-catalytic core component; involved in 3'-5' exoribonuclease processing of rRNA and mRNA<ref name='S000120282'>Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 {{SGDpaper|S000120282}} PMID 17173052</ref><ref name='S000120270'>Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 {{SGDpaper|S000120270}} PMID 17174896</ref><ref name='S000058465'>Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 {{SGDpaper|S000058465}} PMID 9482746</ref><ref name='S000049705'>Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'--&gt;5' exoribonucleases. Cell 91(4):457-66 {{SGDpaper|S000049705}} PMID 9390555</ref><ref name='S000042474'>Mitchell P, et al. (1996) The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes Dev 10(4):502-13
 
  {{SGDpaper|S000042474}} PMID 8600032</ref>
 
  {{SGDpaper|S000042474}} PMID 8600032</ref>
 
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Revision as of 14:05, 12 August 2008

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Systematic name YHR069C
Gene name RRP4
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:234660..233581
Primary SGDID S000001111


Description of YHR069C: Exosome non-catalytic core component; involved in 3'-5' exoribonuclease processing of rRNA and mRNA[1][2][3][4][5]




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References

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  1. Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 SGD PMID 17173052
  2. Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 SGD PMID 17174896
  3. Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
  4. Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
  5. Mitchell P, et al. (1996) The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes Dev 10(4):502-13 SGD PMID 8600032

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