YHL007C

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Systematic name YHL007C
Gene name STE20
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:97933..95114
Primary SGDID S000000999


Description of YHL007C: Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response, pseudohyphal/invasive growth, and vacuole inheritance; GBB motif (found in noncatalytic domains of PAKs) binds Ste4p[1][2][3]




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References

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  1. Bartholomew CR and Hardy CF (2009) p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. Eukaryot Cell 8(4):560-72 SGD PMID 19218422
  2. Peter M, et al. (1996) Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 15(24):7046-59 SGD PMID 9003780
  3. Song J, et al. (2001) Molecular interactions of the Gbeta binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gbeta binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. J Biol Chem 276(44):41205-12 SGD PMID 11509560

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