Difference between revisions of "YGR270W"

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'''Description of YGR270W:''' Protein of unknown function, member of CDC48/PAS1/SEC18 family of ATPases, potentially phosphorylated by Cdc28p<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000044551'>Agostoni Carbone ML, et al. (1998) A 9359 bp fragment from the right arm of Saccharomyces cerevisiae chromosome VII includes the FOL2 and YTA7 genes and three unknown open reading frames. Yeast 14(6):587-91
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'''Description of YGR270W:''' Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p<ref name='S000126475'>Gradolatto A, et al. (2008) Saccharomyces cerevisiae Yta7 Regulates Histone Gene Expression. Genetics 179(1):291-304 {{SGDpaper|S000126475}} PMID 18493054</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000044551'>Agostoni Carbone ML, et al. (1998) A 9359 bp fragment from the right arm of Saccharomyces cerevisiae chromosome VII includes the FOL2 and YTA7 genes and three unknown open reading frames. Yeast 14(6):587-91
 
  {{SGDpaper|S000044551}} PMID 9605509</ref>
 
  {{SGDpaper|S000044551}} PMID 9605509</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YGR270W
Gene name YTA7
Aliases
Feature type ORF, Verified
Coordinates Chr VII:1027376..1031515
Primary SGDID S000003502


Description of YGR270W: Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [4]





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References

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  1. Gradolatto A, et al. (2008) Saccharomyces cerevisiae Yta7 Regulates Histone Gene Expression. Genetics 179(1):291-304 SGD PMID 18493054
  2. 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. Agostoni Carbone ML, et al. (1998) A 9359 bp fragment from the right arm of Saccharomyces cerevisiae chromosome VII includes the FOL2 and YTA7 genes and three unknown open reading frames. Yeast 14(6):587-91 SGD PMID 9605509
  4. submitted by Jeff Ubersax on 2004-01-27

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