YGR233C

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Systematic name YGR233C
Gene name PHO81
Aliases
Feature type ORF, Verified
Coordinates Chr VII:958213..954677
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Description of YGR233C: Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; required for derepression of PHO5; transcriptionally regulated by Pho4p and Pho2p[1][2][3]



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References

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  1. Huang S, et al. (2001) Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Mol Cell Biol 21(19):6695-705 SGD PMID 11533256
  2. Lee M, et al. (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22 SGD PMID 11069666
  3. Creasy CL, et al. (1996) Negative transcriptional regulation of PH081 expression in Saccharomyces cerevisiae. Gene 168(1):23-9 SGD PMID 8626060

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