Difference between revisions of "YGR233C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR233C YGR233C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003465 YGR233C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO81 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO81 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''VAC6, phoS''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr VII:958213..954677
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|nowrap| Chr VII:958210..954674
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003465
 
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'''Description of {{PAGENAME}}:''' Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; required for derepression of PHO5; transcriptionally regulated by Pho4p and Pho2p<ref name='S000066097'>Huang S, et al. (2001) Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Mol Cell Biol 21(19):6695-705 {{SGDpaper|S000066097}} PMID 11533256</ref><ref name='S000059446'>Lee M, et al. (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22 {{SGDpaper|S000059446}} PMID 11069666</ref><ref name='S000041855'>Creasy CL, et al. (1996) Negative transcriptional regulation of PH081 expression in Saccharomyces cerevisiae. Gene 168(1):23-9
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'''Description of YGR233C:''' Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p<ref name='S000041855'>Creasy CL, et al. (1996) Negative transcriptional regulation of PH081 expression in Saccharomyces cerevisiae. Gene 168(1):23-9 {{SGDpaper|S000041855}} PMID 8626060</ref><ref name='S000066097'>Huang S, et al. (2001) Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Mol Cell Biol 21(19):6695-705 {{SGDpaper|S000066097}} PMID 11533256</ref><ref name='S000059446'>Lee M, et al. (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22 {{SGDpaper|S000059446}} PMID 11069666</ref><ref name='S000122147'>Lee YS, et al. (2007) Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science 316(5821):109-12
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  {{SGDpaper|S000041855}} PMID 8626060</ref>
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  {{SGDpaper|S000122147}} PMID 17412959</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== DNA and RNA Details ===
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[[Category:Topic:DNA and RNA Details]]
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==== Other DNA and RNA Details ====
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'''Other Topic''': expression [[Category:Topic:expression]]
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Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. <ref name='S000073646'>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 {{SGDpaper|S000073646}} PMID 12414795</ref> <ref name = 'CAset9153-2003-07-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9153 Viktor Boer] on 2003-07-25</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YGR233C
Gene name PHO81
Aliases VAC6, phoS
Feature type ORF, Verified
Coordinates Chr VII:958210..954674
Primary SGDID S000003465


Description of YGR233C: Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p[1][2][3][4]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [5] [6]




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References

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  1. ↑ Creasy CL, et al. (1996) Negative transcriptional regulation of PH081 expression in Saccharomyces cerevisiae. Gene 168(1):23-9 SGD PMID 8626060
  2. ↑ Huang S, et al. (2001) Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Mol Cell Biol 21(19):6695-705 SGD PMID 11533256
  3. ↑ Lee M, et al. (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22 SGD PMID 11069666
  4. ↑ Lee YS, et al. (2007) Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science 316(5821):109-12 SGD PMID 17412959
  5. ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. ↑ submitted by Viktor Boer on 2003-07-25

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