Difference between revisions of "YGR195W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR195W YGR195W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003427 YGR195W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SKI6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SKI6 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VII:888887..889627
 
|nowrap| Chr VII:888887..889627
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003427
 
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'''Description of {{PAGENAME}}:''' 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs<ref name='S000058465'>Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 {{SGDpaper|S000058465}} PMID 9482746</ref><ref name='S000049705'>Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'--&gt;5' exoribonucleases. Cell 91(4):457-66 {{SGDpaper|S000049705}} PMID 9390555</ref><ref name='S000045137'>Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96
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'''Description of YGR195W:''' 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs<ref name='S000058465'>Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 {{SGDpaper|S000058465}} PMID 9482746</ref><ref name='S000049705'>Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'--&gt;5' exoribonucleases. Cell 91(4):457-66 {{SGDpaper|S000049705}} PMID 9390555</ref><ref name='S000045137'>Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96
 
  {{SGDpaper|S000045137}} PMID 9566888</ref>
 
  {{SGDpaper|S000045137}} PMID 9566888</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YGR195W
Gene name SKI6
Aliases ECM20, RRP41
Feature type ORF, Verified
Coordinates Chr VII:888887..889627
Primary SGDID S000003427


Description of YGR195W: 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs[1][2][3]




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References

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  1. Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
  2. Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
  3. Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96 SGD PMID 9566888

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