Difference between revisions of "YGR155W"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (11 intermediate revisions by the same user not shown) | |||
| Line 4: | Line 4: | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003387 YGR155W] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYS4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYS4 '' | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:798543..800066 |
| + | |- | ||
| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003387 | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YGR155W:''' Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog cause homocystinuria<ref name='S000148801'>Hoose SA, et al. (2012) A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division. PLoS Genet 8(3):e1002590 {{SGDpaper|S000148801}} PMID 22438835</ref><ref name='S000052237'>Ono B, et al. (1988) Cysteine biosynthesis in Saccharomyces cerevisiae: mutation that confers cystathionine beta-synthase deficiency. J Bacteriol 170(12):5883-9 {{SGDpaper|S000052237}} PMID 3056921</ref><ref name='S000042385'>Ono B, et al. (1994) Purification and properties of Saccharomyces cerevisiae cystathionine beta-synthase. Yeast 10(3):333-9 {{SGDpaper|S000042385}} PMID 8017103</ref><ref name='S000062636'>Shan X and Kruger WD (1998) Correction of disease-causing CBS mutations in yeast. Nat Genet 19(1):91-3 {{SGDpaper|S000062636}} PMID 9590298</ref><ref name='S000130695'>Singh S, et al. (2009) Relative Contributions of Cystathionine {beta}-Synthase and {gamma}-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions. J Biol Chem 284(33):22457-66 |
| − | {{SGDpaper| | + | {{SGDpaper|S000130695}} PMID 19531479</ref> |
<br> | <br> | ||
<br> | <br> | ||
| Line 27: | Line 29: | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| + | <!-- | ||
| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
| + | --> | ||
| + | |||
Latest revision as of 14:05, 26 March 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR155W |
| Gene name | CYS4 |
| Aliases | NHS5, STR4, VMA41 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:798543..800066 |
| Primary SGDID | S000003387 |
Description of YGR155W: Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog cause homocystinuria[1][2][3][4][5]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Hoose SA, et al. (2012) A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division. PLoS Genet 8(3):e1002590 SGD PMID 22438835
- ↑ Ono B, et al. (1988) Cysteine biosynthesis in Saccharomyces cerevisiae: mutation that confers cystathionine beta-synthase deficiency. J Bacteriol 170(12):5883-9 SGD PMID 3056921
- ↑ Ono B, et al. (1994) Purification and properties of Saccharomyces cerevisiae cystathionine beta-synthase. Yeast 10(3):333-9 SGD PMID 8017103
- ↑ Shan X and Kruger WD (1998) Correction of disease-causing CBS mutations in yeast. Nat Genet 19(1):91-3 SGD PMID 9590298
- ↑ Singh S, et al. (2009) Relative Contributions of Cystathionine {beta}-Synthase and {gamma}-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions. J Biol Chem 284(33):22457-66 SGD PMID 19531479
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
