Difference between revisions of "YGR150C"

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'''Description of YGR150C:''' Protein of unknown function, contains PPR motifs; mutant has growth defects on both non-fermentable carbon sources and rich medium; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies<ref name='S000124675'>Golik P (2007)    {{SGDpaper|S000124675}} PMID </ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000080907'>Deutschbauer AM, et al. (2005) Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169(4):1915-25 {{SGDpaper|S000080907}} PMID 15716499</ref><ref name='S000076000'>Ellis TP, et al. (2004) Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae. J Biol Chem 279(16):15728-33 {{SGDpaper|S000076000}} PMID 14742425</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000072525'>Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
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'''Description of YGR150C:''' Protein of unknown function containing pentatricopeptide repeat (PPR) motif; mutant is respiratory deficient and has defective plasma membrane electron transport; authentic non-tagged protein is detected in highly purified mitochondria<ref name='S000071517'>Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 {{SGDpaper|S000071517}} PMID 11907266</ref><ref name='S000072525'>Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 {{SGDpaper|S000072525}} PMID 12134146</ref><ref name='S000076000'>Ellis TP, et al. (2004) Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae. J Biol Chem 279(16):15728-33 {{SGDpaper|S000076000}} PMID 14742425</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000127282'>Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
  {{SGDpaper|S000072525}} PMID 12134146</ref>
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  {{SGDpaper|S000127282}} PMID 18657191</ref>
 
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Revision as of 04:15, 19 December 2008

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Systematic name YGR150C
Gene name DMR1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:793058..790464
Primary SGDID S000003382


Description of YGR150C: Protein of unknown function containing pentatricopeptide repeat (PPR) motif; mutant is respiratory deficient and has defective plasma membrane electron transport; authentic non-tagged protein is detected in highly purified mitochondria[1][2][3][4][5]




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References

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  1. Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
  2. Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 SGD PMID 12134146
  3. Ellis TP, et al. (2004) Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae. J Biol Chem 279(16):15728-33 SGD PMID 14742425
  4. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  5. Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905 SGD PMID 18657191

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