Difference between revisions of "YGR144W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 04:32, 21 May 2007

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Systematic name YGR144W
Gene name THI4
Aliases ESP35, MOL1
Feature type ORF, Verified
Coordinates Chr VII:780404..781384
Primary SGDID S000003376


Description of YGR144W: Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability[1][2][3]




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References

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  1. Chatterjee A, et al. (2007) Biosynthesis of Thiamin Thiazole in Eukaryotes: Conversion of NAD to an Advanced Intermediate. J Am Chem Soc 129(10):2914-22 SGD PMID 17309261
  2. Machado CR, et al. (1997) Dual role for the yeast THI4 gene in thiamine biosynthesis and DNA damage tolerance. J Mol Biol 273(1):114-21 SGD PMID 9367751
  3. Praekelt UM, et al. (1994) Regulation of THI4 (MOL1), a thiamine-biosynthetic gene of Saccharomyces cerevisiae. Yeast 10(4):481-90 SGD PMID 7941734

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