Difference between revisions of "YGR110W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003342 YGR110W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003342 YGR110W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CLD1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CLD1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:713713..715050
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|nowrap| Chr VII:713709..715046
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003342
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003342
 
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'''Description of YGR110W:''' Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58<ref name='S000129440'>Beranek A, et al. (2009) Identification of a cardiolipin-specific phospholipase encoded by the gene CLD1 (YGR110W) in yeast. J Biol Chem {{SGDpaper|S000129440}} PMID 19244244</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 {{SGDpaper|S000125260}} PMID 18202368</ref><ref name='S000081656'>Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46
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'''Description of YGR110W:''' Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58<ref name='S000129440'>Beranek A, et al. (2009) Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. J Biol Chem 284(17):11572-8 {{SGDpaper|S000129440}} PMID 19244244</ref><ref name='S000081656'>Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 {{SGDpaper|S000081656}} PMID 15878181</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214
  {{SGDpaper|S000081656}} PMID 15878181</ref>
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  {{SGDpaper|S000125260}} PMID 18202368</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGR110W
Gene name CLD1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:713709..715046
Primary SGDID S000003342


Description of YGR110W: Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58[1][2][3]




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References

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  1. Beranek A, et al. (2009) Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. J Biol Chem 284(17):11572-8 SGD PMID 19244244
  2. Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 SGD PMID 15878181
  3. Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368

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