Difference between revisions of "YGR110W"
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| − | '''Description of YGR110W:''' Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58<ref name='S000081656'>Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 {{SGDpaper|S000081656}} PMID 15878181</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 {{SGDpaper|S000125260}} PMID 18202368</ref><ref name='S000129440'>Beranek A, et al. (2009) Identification of a | + | '''Description of YGR110W:''' Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58<ref name='S000081656'>Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 {{SGDpaper|S000081656}} PMID 15878181</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 {{SGDpaper|S000125260}} PMID 18202368</ref><ref name='S000129440'>Beranek A, et al. (2009) Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. J Biol Chem 284(17):11572-8 |
{{SGDpaper|S000129440}} PMID 19244244</ref> | {{SGDpaper|S000129440}} PMID 19244244</ref> | ||
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Revision as of 13:05, 25 April 2009
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| Systematic name | YGR110W |
| Gene name | CLD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:713713..715050 |
| Primary SGDID | S000003342 |
Description of YGR110W: Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58[1][2][3]
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References
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- ↑ Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 SGD PMID 15878181
- ↑ Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368
- ↑ Beranek A, et al. (2009) Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. J Biol Chem 284(17):11572-8 SGD PMID 19244244
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