Difference between revisions of "YGR104C"
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| − | '''Description of YGR104C:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance<ref name=' | + | '''Description of YGR104C:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance<ref name='S000043970'>Thompson CM, et al. (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73(7):1361-75 {{SGDpaper|S000043970}} PMID 8324825</ref><ref name='S000053959'>Kim YJ, et al. (1994) A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77(4):599-608 {{SGDpaper|S000053959}} PMID 8187178</ref><ref name='S000082023'>Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 {{SGDpaper|S000082023}} PMID 15896740</ref><ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 |
| − | {{SGDpaper| | + | {{SGDpaper|S000114270}} PMID 15161972</ref> |
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Revision as of 04:15, 19 December 2008
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| Systematic name | YGR104C |
| Gene name | SRB5 |
| Aliases | MED18 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:698372..697449 |
| Primary SGDID | S000003336 |
Description of YGR104C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance[1][2][3][4]
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References
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- ↑ Thompson CM, et al. (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73(7):1361-75 SGD PMID 8324825
- ↑ Kim YJ, et al. (1994) A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77(4):599-608 SGD PMID 8187178
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
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