Difference between revisions of "YGR101W"
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| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Function/Process ==== | ||
| + | [[Category:Topic:Protein Details:Protein Function/Process]] | ||
| + | Limited proteolysis of Mgm1p generating the short isoform of Mgm1p depends on the mitochondrial rhomboid protease Pcp1p. Lack of Pcp1p can partially be complemented by expression of an artificial variant of the short isoform of Mgm1p. <ref name='S000073854'>Herlan M, et al. (2003) Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J Biol Chem 278(30):27781-8 {{SGDpaper|S000073854}} PMID 12707284</ref> <ref name = 'CAset9617-2003-09-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9617 Andreas Reichert] on 2003-09-25</ref> | ||
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| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Function/Process ==== | ||
| + | [[Category:Topic:Protein Details:Protein Function/Process]] | ||
| + | |||
| + | Limited proteolysis of Mgm1p generating the short isoform of Mgm1p depends on the mitochondrial rhomboid protease Pcp1p. Lack of Pcp1p can partially be complemented by expression of an artificial variant of the short isoform of Mgm1p. <ref name='S000073854'>Herlan M, et al. (2003) Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J Biol Chem 278(30):27781-8 {{SGDpaper|S000073854}} PMID 12707284</ref> <ref name = 'CAset9617-2003-09-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9617 Andreas Reichert] on 2003-09-25</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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Revision as of 17:05, 23 January 2007
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| Systematic name | YGR101W | |
| Gene name | PCP1 | |
| Aliases | MDM37, RBD1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:693367..694407 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YGR101W: Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases[1][2][3]
Protein Details
Protein Function/Process
Limited proteolysis of Mgm1p generating the short isoform of Mgm1p depends on the mitochondrial rhomboid protease Pcp1p. Lack of Pcp1p can partially be complemented by expression of an artificial variant of the short isoform of Mgm1p. [2] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Function/Process
Limited proteolysis of Mgm1p generating the short isoform of Mgm1p depends on the mitochondrial rhomboid protease Pcp1p. Lack of Pcp1p can partially be complemented by expression of an artificial variant of the short isoform of Mgm1p. [2] [4]
References
See Help:References on how to add references
- ↑ Sesaki H, et al. (2003) Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion. Biochem Biophys Res Commun 308(2):276-83 SGD PMID 12901865
- ↑ 2.0 2.1 2.2 Herlan M, et al. (2003) Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J Biol Chem 278(30):27781-8 SGD PMID 12707284
- ↑ Esser K, et al. (2002) A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. J Mol Biol 323(5):835-43 SGD PMID 12417197
- ↑ 4.0 4.1 submitted by Andreas Reichert on 2003-09-25
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