Difference between revisions of "YGR092W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YGR092W
Gene name DBF2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:668193..669911


Description of YGR092W: Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]




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References

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  1. Visintin R and Amon A (2001) Regulation of the mitotic exit protein kinases Cdc15 and Dbf2. Mol Biol Cell 12(10):2961-74 SGD PMID 11598184
  2. Frenz LM, et al. (2000) The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis. J Cell Sci 113 Pt 19():3399-408 SGD PMID 10984431
  3. Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 SGD PMID 8131744
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-27

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