Difference between revisions of "YGR092W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003324 YGR092W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DBF2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DBF2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:668189..669907 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003324 |
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| − | '''Description of | + | '''Description of YGR092W:''' Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs<ref name='S000059285'>Frenz LM, et al. (2000) The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis. J Cell Sci 113 Pt 19():3399-408 {{SGDpaper|S000059285}} PMID 10984431</ref><ref name='S000048013'>Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 {{SGDpaper|S000048013}} PMID 8131744</ref><ref name='S000147928'>Trcek T, et al. (2011) Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell 147(7):1484-97 {{SGDpaper|S000147928}} PMID 22196726</ref><ref name='S000074821'>Visintin R and Amon A (2001) Regulation of the mitotic exit protein kinases Cdc15 and Dbf2. Mol Biol Cell 12(10):2961-74 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074821}} PMID 11598184</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
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| + | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-27</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 14:05, 14 May 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR092W |
| Gene name | DBF2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:668189..669907 |
| Primary SGDID | S000003324 |
Description of YGR092W: Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs[1][2][3][4]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Frenz LM, et al. (2000) The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis. J Cell Sci 113 Pt 19():3399-408 SGD PMID 10984431
- ↑ Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 SGD PMID 8131744
- ↑ Trcek T, et al. (2011) Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell 147(7):1484-97 SGD PMID 22196726
- ↑ Visintin R and Amon A (2001) Regulation of the mitotic exit protein kinases Cdc15 and Dbf2. Mol Biol Cell 12(10):2961-74 SGD PMID 11598184
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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