YGR063C

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Systematic name YGR063C
Gene name SPT4
Aliases
Feature type ORF, Verified
Coordinates Chr VII:617828..617520
Primary SGDID S000003295


Description of YGR063C: Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing[1][2][3][4]




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References

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  1. SGD (2007) Information without a citation in SGD SGD PMID
  2. Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 SGD PMID 12554661
  3. Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 SGD PMID 12556496
  4. Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91 SGD PMID 11173517

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