YGR062C
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| Systematic name | YGR062C |
| Gene name | COX18 |
| Aliases | OXA2 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:617282..616332 |
| Primary SGDID | S000003294 |
Description of YGR062C: Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC[1][2][3][4][5]
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References
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- ↑ Souza RL, et al. (2000) Cloning and characterization of COX18, a Saccharomyces cerevisiae PET gene required for the assembly of cytochrome oxidase. J Biol Chem 275(20):14898-902 SGD PMID 10809734
- ↑ Saracco SA and Fox TD (2002) Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane. Mol Biol Cell 13(4):1122-31 SGD PMID 11950926
- ↑ Fiumera HL, et al. (2007) Translocation of mitochondrially synthesized Cox2 domains from the matrix to the intermembrane space. Mol Cell Biol 27(13):4664-73 SGD PMID 17452441
- ↑ van Bloois E, et al. (2007) Saccharomyces cerevisiae Cox18 complements the essential Sec-independent function of Escherichia coli YidC. FEBS J 274(21):5704-13 SGD PMID 17922846
- ↑ Fiumera HL, et al. (2009) Translocation and Assembly of Mitochondrially Coded Saccharomyces cerevisiae Cytochrome c Oxidase Subunit Cox2 by Oxa1 and Yme1, in the Absence of Cox18. Genetics SGD PMID 19307606
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