Difference between revisions of "YGR048W"

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'''Description of YGR048W:''' Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol<ref name='S000071485'>Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 {{SGDpaper|S000071485}} PMID 12015140</ref><ref name='S000069703'>Braun S, et al. (2002) Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J 21(4):615-21 {{SGDpaper|S000069703}} PMID 11847109</ref><ref name='S000069082'>Ye Y, et al. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414(6864):652-6
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'''Description of YGR048W:''' Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol<ref name='S000069082'>Ye Y, et al. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414(6864):652-6 {{SGDpaper|S000069082}} PMID 11740563</ref><ref name='S000069703'>Braun S, et al. (2002) Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J 21(4):615-21 {{SGDpaper|S000069703}} PMID 11847109</ref><ref name='S000071485'>Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71
  {{SGDpaper|S000069082}} PMID 11740563</ref>
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  {{SGDpaper|S000071485}} PMID 12015140</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YGR048W
Gene name UFD1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:589830..590915
Primary SGDID S000003280


Description of YGR048W: Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol[1][2][3]




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References

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  1. Ye Y, et al. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414(6864):652-6 SGD PMID 11740563
  2. Braun S, et al. (2002) Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J 21(4):615-21 SGD PMID 11847109
  3. Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 SGD PMID 12015140

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