Difference between revisions of "YGR014W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YGR014W
Gene name MSB2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:516947..520867


Description of YGR014W: Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate[1][2][3][4]




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Community Commentary

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [5]


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References

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  1. Cullen PJ, et al. (2004) A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 18(14):1695-708 SGD PMID 15256499
  2. 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. O'Rourke SM and Herskowitz I (2002) A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol 22(13):4739-49 SGD PMID 12052881
  4. Bender A and Pringle JR (1989) Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1. Proc Natl Acad Sci U S A 86(24):9976-80 SGD PMID 2690082
  5. submitted by Jeff Ubersax on 2004-01-27

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