Difference between revisions of "YGL253W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003222 YGL253W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HXK2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HXK2 '' | ||
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|nowrap| Chr VII:23935..25395 | |nowrap| Chr VII:23935..25395 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003222 |
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| − | '''Description of | + | '''Description of YGL253W:''' Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene<ref name='S000073626'>Bianconi ML (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13 {{SGDpaper|S000073626}} PMID 12611889</ref><ref name='S000060187'>Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 |
{{SGDpaper|S000060187}} PMID 11311123</ref> | {{SGDpaper|S000060187}} PMID 11311123</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YGL253W |
| Gene name | HXK2 |
| Aliases | HEX1, HKB, SCI2 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:23935..25395 |
| Primary SGDID | S000003222 |
Description of YGL253W: Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene[1][2]
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Community Commentary
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References
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- ↑ Bianconi ML (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13 SGD PMID 12611889
- ↑ Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 SGD PMID 11311123
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