Difference between revisions of "YGL253W"

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'''Description of YGL253W:''' Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene<ref name='S000060187'>Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 {{SGDpaper|S000060187}} PMID 11311123</ref><ref name='S000073626'>Bianconi ML (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13
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'''Description of YGL253W:''' Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene<ref name='S000073626'>Bianconi ML (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13 {{SGDpaper|S000073626}} PMID 12611889</ref><ref name='S000060187'>Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31
{{SGDpaper|S000073626}} PMID 12611889</ref>
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{{SGDpaper|S000060187}} PMID 11311123</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YGL253W
Gene name HXK2
Aliases HEX1, HKB, SCI2
Feature type ORF, Verified
Coordinates Chr VII:23935..25395
Primary SGDID S000003222


Description of YGL253W: Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene[1][2]




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References

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  1. Bianconi ML (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13 SGD PMID 12611889
  2. Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 SGD PMID 11311123

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