YGL220W

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Systematic name YGL220W
Gene name FRA2
Aliases AIM15
Feature type ORF, Uncharacterized
Coordinates Chr VII:82373..82735
Primary SGDID S000003188


Description of YGL220W: Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; null mutant fails to repress iron regulon and is sensitive to nickel[1][2][3]




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References

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  1. Kumanovics A, et al. (2008) Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis. J Biol Chem 283(16):10276-86 SGD PMID 18281282
  2. Bishop AL, et al. (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol 63(2):507-20 SGD PMID 17176259
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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