Difference between revisions of "YGL219C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003187 YGL219C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003187 YGL219C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDM34 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDM34 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:84256..82877
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|nowrap| Chr VII:84257..82878
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003187
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003187
 
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'''Description of YGL219C:''' Mitochondrial outer membrane protein required for normal mitochondrial morphology and inheritance; localizes to dots on mitochondrial surface near mtDNA nucleoids; ubiquitination target of Mdm30p; interacts genetically with MDM31 and MDM32<ref name='S000080209'>Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 {{SGDpaper|S000080209}} PMID 15631992</ref><ref name='S000076174'>Youngman MJ, et al. (2004) Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 164(5):677-88 {{SGDpaper|S000076174}} PMID 14981098</ref><ref name='S000127748'>Ota K, et al. (2008) A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p. Genes Cells 13(10):1075-85
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'''Description of YGL219C:''' Mitochondrial component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth<ref name='S000080209'>Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 {{SGDpaper|S000080209}} PMID 15631992</ref><ref name='S000132272'>Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 {{SGDpaper|S000132272}} PMID 19556461</ref><ref name='S000127748'>Ota K, et al. (2008) A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p. Genes Cells 13(10):1075-85 {{SGDpaper|S000127748}} PMID 18775025</ref><ref name='S000076174'>Youngman MJ, et al. (2004) Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 164(5):677-88
  {{SGDpaper|S000127748}} PMID 18775025</ref>
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  {{SGDpaper|S000076174}} PMID 14981098</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL219C
Gene name MDM34
Aliases MMM2
Feature type ORF, Verified
Coordinates Chr VII:84257..82878
Primary SGDID S000003187


Description of YGL219C: Mitochondrial component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth[1][2][3][4]




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References

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  1. Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 SGD PMID 15631992
  2. Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 SGD PMID 19556461
  3. Ota K, et al. (2008) A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p. Genes Cells 13(10):1075-85 SGD PMID 18775025
  4. Youngman MJ, et al. (2004) Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 164(5):677-88 SGD PMID 14981098

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