Difference between revisions of "YGL207W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YGL207W
Gene name SPT16
Aliases CDC68, SSF1
Feature type ORF, Verified
Coordinates Chr VII:98973..102080


Description of YGL207W: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure[1][2]




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References

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  1. Belotserkovskaya R, et al. (2003) FACT facilitates transcription-dependent nucleosome alteration. Science 301(5636):1090-3 SGD PMID 12934006
  2. Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 SGD PMID 12524332

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