Difference between revisions of "YGL207W"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:98969..102076 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003175 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003175 | ||
Revision as of 14:05, 3 February 2011
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| Systematic name | YGL207W |
| Gene name | SPT16 |
| Aliases | CDC68, SSF1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:98969..102076 |
| Primary SGDID | S000003175 |
Description of YGL207W: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases[1][2][3][4]
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References
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- ↑ Belotserkovskaya R, et al. (2003) FACT facilitates transcription-dependent nucleosome alteration. Science 301(5636):1090-3 SGD PMID 12934006
- ↑ Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 SGD PMID 12524332
- ↑ Ransom M, et al. (2009) FACT and the Proteasome Promote Promoter Chromatin Disassembly and Transcriptional Initiation. J Biol Chem 284(35):23461-71 SGD PMID 19574230
- ↑ Xin H, et al. (2009) yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement. Mol Cell 35(3):365-76 SGD PMID 19683499
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